Age-related macular degeneration is the leading cause of irreversible blindness in Americans over 60 years of age. In October 2001, the National Eye Institute (NEI) one of the Federal Government's National Institutes of Health (NIH) completed a large ten-year study. The Age-Related Eye Disease Study (AREDS) proved that a special formula of antioxidant vitamins plus zinc slowed the progression of Age-Related Macular Degeneration (AMD) by 25 percent. High doses of beta-carotene have been shown to increase the risk of lung cancer amoung smokers. Our Smoker's Advanced Formula is specially developed for smokers. It contains the exact AREDS recommended dosage with NO beta-carotene in just two easy to swallow capsules daily. Our AREDS Smoker's Advanced formula also contains the benefit of 10mg of FloraGLO® lutein, an antioxidant carotenoid found in fruits and green leafy vegetables as well as the macular region of the healthy retina. Also included are 3.5mg of Zeaxathin, 20 mg of Bilberry, 25 mg of Grape Seed Extract, and 25 mg of Alpha Lipoic Acid. Zeaxanthin also is not made by the body and high levels can only be obtained from supplements. Like lutein, zeaxanthin is found in the macula, however it is much more concentrated in the center part of the macula compared to lutein. Our Smoker's Advanced formula contains OPTISHARP™ brand zeaxanthin from DSM (formerly Roche Vitamins). Our AREDS Smoker's Advanced is made with Natural Vitamin E. AREDS Smoker's Advanced comes in a 180 easy to swallow capsule (3 month supply) bottle. Supplement Facts: Vitamin C (Ascorbic Acid) - 500mg Vitamin E (as Natural d-Alpha Tocopheryl Succinate) - 400IU Zinc (as Zinc Oxide) - 80mg Copper (as Cupric Oxide) - 2mg Lutein (10mg) Zeaxanthin (3.5mg) Bilberry Standardized Extract (40mg) Grape Seed Extract (50mg) Alpha-Lipoic Acid (50mg) Our product line was developed from the latest published studies and clinical research. Our manufacturing process adheres to the strictest Goods Manufacturing Practices (GMPs) and follows all applicable United States Pharmacopea (USP) guidelines. All AREDS Oral Products are produced by factory on an as odered basis and takes 4 to 6 weeks to make it to your door. We strive to get your order to you before that time frame.